Ahmad Hariri, PhD - Publications - Institute for Genome Sciences & Policy

Ventral Striatum Reactivity to Reward and Recent Life Stress Interact to Predict Positive Affect.

Nikolova YS, Bogdan R, Brigidi BD, Hariri AR, Biol Psychiatry. 2012 Apr 23;. Abstract

Toward a Mechanistic Understanding of How Variability in Neurobiology Shapes Individual Differences in Behavior.

Bogdan R, Carré JM, Hariri AR, Curr Top Behav Neurosci. 2012 Mar 23;. Abstract

Mineralocorticoid Receptor Iso/Val (rs5522) Genotype Moderates the Association Between Previous Childhood Emotional Neglect and Amygdala Reactivity.

Bogdan R, Williamson DE, Hariri AR, Am J Psychiatry. 2012 Mar 8;. Abstract

Neural Mechanisms Underlying 5-HTTLPR-Related Sensitivity to Acute Stress.

Drabant EM, Ramel W, Edge MD, Hyde LW, Kuo JR, Goldin PR, Hariri AR, Gross JJ, Am J Psychiatry. 2012 Apr 1;169(4):397-405. Abstract

Using confirmatory factor analysis to measure contemporaneous activation of defined neuronal networks in functional magnetic resonance imaging.

Lahey BB, McNealy K, Knodt A, Zald DH, Sporns O, Manuck SB, Flory JD, Applegate B, Rathouz PJ, Hariri AR, Neuroimage. 2012 May 1;60(4):1982-91. Abstract

Imaging genetics and the neurobiological basis of individual differences in vulnerability to addiction.

Sweitzer MM, Donny EC, Hariri AR, Drug Alcohol Depend. 2012 Feb 16;. Abstract

Adenylate cyclase 7 is implicated in the biology of depression and modulation of affective neural circuitry.

Joeyen-Waldorf J, Nikolova YS, Edgar N, Walsh C, Kota R, Lewis DA, Ferrell R, Manuck SB, Hariri AR, Sibille E, Biol Psychiatry. 2012 Apr 1;71(7):627-32. Abstract

What lies beneath the face of aggression?

Carré JM, Murphy KR, Hariri AR, Soc Cogn Affect Neurosci. 2011 Dec 23;. Abstract

Genetic and hormonal sensitivity to threat: Testing a serotonin transporter genotype×testosterone interaction.

Josephs RA, Telch MJ, Hixon JG, Evans JJ, Lee H, Knopik VS, McGeary JE, Hariri AR, Beevers CG, Psychoneuroendocrinology. 2012 Jun;37(6):752-61. Abstract

Understanding risk for psychopathology through imaging gene-environment interactions.

Hyde LW, Bogdan R, Hariri AR, Trends Cogn Sci. 2011 Sep;15(9):417-27. Abstract

The what, where, and when of catechol-O-methyltransferase.

Hariri AR, Biol Psychiatry. 2011 Aug 1;70(3):214-5. Abstract

Multilocus genetic profile for dopamine signaling predicts ventral striatum reactivity.

Nikolova YS, Ferrell RE, Manuck SB, Hariri AR, Neuropsychopharmacology. 2011 Aug;36(9):1940-7. Abstract

Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder.

Morey RA, Hariri AR, Gold AL, Hauser MA, Munger HJ, Dolcos F, McCarthy G, BMC Psychiatry. 2011;11:76. Abstract

The amygdala: inside and out.

Hariri AR, Whalen PJ, F1000 Biol Rep. 2011;3:2. Abstract

The social neuroendocrinology of human aggression.

Carré JM, McCormick CM, Hariri AR, Psychoneuroendocrinology. 2011 Aug;36(7):935-44. Abstract

Associations between serotonin transporter gene promoter region (5-HTTLPR) polymorphism and gaze bias for emotional information.

Beevers CG, Marti CN, Lee HJ, Stote DL, Ferrell RE, Hariri AR, Telch MJ, J Abnorm Psychol. 2011 Feb;120(1):187-97. Abstract

Interaction between trait anxiety and trait anger predict amygdala reactivity to angry facial expressions in men but not women.

Carré JM, Fisher PM, Manuck SB, Hariri AR, Soc Cogn Affect Neurosci. 2012 Feb;7(2):213-21. Abstract

Experiential, autonomic, and neural responses during threat anticipation vary as a function of threat intensity and neuroticism.

Drabant EM, Kuo JR, Ramel W, Blechert J, Edge MD, Cooper JR, Goldin PR, Hariri AR, Gross JJ, Neuroimage. 2011 Mar 1;55(1):401-10. Abstract

Perceived social support moderates the link between threat-related amygdala reactivity and trait anxiety.

Hyde LW, Gorka A, Manuck SB, Hariri AR, Neuropsychologia. 2011 Mar;49(4):651-6. Abstract

Parental education predicts corticostriatal functionality in adulthood.

Gianaros PJ, Manuck SB, Sheu LK, Kuan DC, Votruba-Drzal E, Craig AE, Hariri AR, Cereb Cortex. 2011 Apr;21(4):896-910. Abstract

Theory and methods in cultural neuroscience.

Chiao JY, Hariri AR, Harada T, Mano Y, Sadato N, Parrish TB, Iidaka T, Soc Cogn Affect Neurosci. 2010 Jun;5(2-3):356-61. Abstract

Genetic polymorphisms: a cornerstone of translational biobehavioral research.

Hariri AR, Sci Transl Med. 2010 Feb 10;2(18):18ps6. Abstract

Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits.

Caspi A, Hariri AR, Holmes A, Uher R, Moffitt TE, Am J Psychiatry. 2010 May;167(5):509-27. Abstract

Amygdala reactivity is inversely related to level of cannabis use in individuals with comorbid cannabis dependence and major depression.

Cornelius JR, Aizenstein HJ, Hariri AR, Addict Behav. 2010 Jun;35(6):644-6. Abstract

Differential patterns of initial and sustained responses in amygdala and cortical regions to emotional stimuli in schizophrenia patients and healthy participants.

Salgado-Pineda P, Fakra E, Delaveau P, Hariri AR, Blin O, J Psychiatry Neurosci. 2010 Jan;35(1):41-8. Abstract

Abnormalities in neural processing of emotional stimuli in Williams syndrome vary according to social vs. non-social content.

Muñoz KE, Meyer-Lindenberg A, Hariri AR, Mervis CB, Mattay VS, Morris CA, Berman KF, Neuroimage. 2010 Mar;50(1):340-6. Abstract

Preferential amygdala reactivity to the negative assessment of neutral faces.

Blasi G, Hariri AR, Alce G, Taurisano P, Sambataro F, Das S, Bertolino A, Weinberger DR, Mattay VS, Biol Psychiatry. 2009 Nov 1;66(9):847-53. Abstract

Salivary testosterone and a trinucleotide (CAG) length polymorphism in the androgen receptor gene predict amygdala reactivity in men.

Manuck SB, Marsland AL, Flory JD, Gorka A, Ferrell RE, Hariri AR, Psychoneuroendocrinology. 2010 Jan;35(1):94-104. Abstract

The neurobiology of individual differences in complex behavioral traits.

Hariri AR, Annu Rev Neurosci. 2009;32:225-47. Abstract

Medial prefrontal cortex 5-HT(2A) density is correlated with amygdala reactivity, response habituation, and functional coupling.

Fisher PM, Meltzer CC, Price JC, Coleman RL, Ziolko SK, Becker C, Moses-Kolko EL, Berga SL, Hariri AR, Cereb Cortex. 2009 Nov;19(11):2499-507. Abstract

Imaging genetics.

Muñoz KE, Hyde LW, Hariri AR, J Am Acad Child Adolesc Psychiatry. 2009 Apr;48(4):356-61. Abstract

Genetic vulnerability to affective psychopathology in childhood: a combined voxel-based morphometry and functional magnetic resonance imaging study.

Mechelli A, Tognin S, McGuire PK, Prata D, Sartori G, Fusar-Poli P, De Brito S, Hariri AR, Viding E, Biol Psychiatry. 2009 Aug 1;66(3):231-7. Abstract

Effects of HTR1A C(-1019)G on amygdala reactivity and trait anxiety.

Fakra E, Hyde LW, Gorka A, Fisher PM, Muñoz KE, Kimak M, Halder I, Ferrell RE, Manuck SB, Hariri AR, Arch Gen Psychiatry. 2009 Jan;66(1):33-40. Abstract

Divergent effects of genetic variation in endocannabinoid signaling on human threat- and reward-related brain function.

Hariri AR, Gorka A, Hyde LW, Kimak M, Halder I, Ducci F, Ferrell RE, Goldman D, Manuck SB, Biol Psychiatry. 2009 Jul 1;66(1):9-16. Abstract

Evidence that altered amygdala activity in schizophrenia is related to clinical state and not genetic risk.

Rasetti R, Mattay VS, Wiedholz LM, Kolachana BS, Hariri AR, Callicott JH, Meyer-Lindenberg A, Weinberger DR, Am J Psychiatry. 2009 Feb;166(2):216-25. Abstract

New perspectives on techniques for the clinical psychiatrist: Brain stimulation, chronobiology and psychiatric brain imaging.

Zanardi R, Barbini B, Rossini D, Bernasconi A, Fregni F, Padberg F, Rossi S, Wirz-Justice A, Terman M, Martiny K, Bersani G, Hariri AR, Pezawas L, Roiser JP, Bertolino A, Calabrese G, Magri L, Benedetti F, Pontiggia A, Malaguti A, Smeraldi E, Colombo C, Psychiatry Clin Neurosci. 2008 Dec;62(6):627-37. Abstract

Altered striatal activation predicting real-world positive affect in adolescent major depressive disorder.

Forbes EE, Hariri AR, Martin SL, Silk JS, Moyles DL, Fisher PM, Brown SM, Ryan ND, Birmaher B, Axelson DA, Dahl RE, Am J Psychiatry. 2009 Jan;166(1):64-73. Abstract

Preclinical atherosclerosis covaries with individual differences in reactivity and functional connectivity of the amygdala.

Gianaros PJ, Hariri AR, Sheu LK, Muldoon MF, Sutton-Tyrrell K, Manuck SB, Biol Psychiatry. 2009 Jun 1;65(11):943-50. Abstract

Dopamine in amygdala gates limbic processing of aversive stimuli in humans.

Kienast T, Hariri AR, Schlagenhauf F, Wrase J, Sterzer P, Buchholz HG, Smolka MN, Gründer G, Cumming P, Kumakura Y, Bartenstein P, Dolan RJ, Heinz A, Nat Neurosci. 2008 Dec;11(12):1381-2. Abstract

Individual differences in typical reappraisal use predict amygdala and prefrontal responses.

Drabant EM, McRae K, Manuck SB, Hariri AR, Gross JJ, Biol Psychiatry. 2009 Mar 1;65(5):367-73. Abstract

Potential neural embedding of parental social standing.

Gianaros PJ, Horenstein JA, Hariri AR, Sheu LK, Manuck SB, Matthews KA, Cohen S, Soc Cogn Affect Neurosci. 2008 Jun;3(2):91-6. Abstract

Interleukin-6 covaries inversely with hippocampal grey matter volume in middle-aged adults.

Marsland AL, Gianaros PJ, Abramowitch SM, Manuck SB, Hariri AR, Biol Psychiatry. 2008 Sep 15;64(6):484-90. Abstract

Acute 5-HT reuptake blockade potentiates human amygdala reactivity.

Bigos KL, Pollock BG, Aizenstein HJ, Fisher PM, Bies RR, Hariri AR, Neuropsychopharmacology. 2008 Dec;33(13):3221-5. Abstract

Perigenual anterior cingulate morphology covaries with perceived social standing.

Gianaros PJ, Horenstein JA, Cohen S, Matthews KA, Brown SM, Flory JD, Critchley HD, Manuck SB, Hariri AR, Soc Cogn Affect Neurosci. 2007 Sep;2(3):161-73. Abstract

Identification of neurogenetic pathways of risk for psychopathology.

Fisher PM, Muñoz KE, Hariri AR, Am J Med Genet C Semin Med Genet. 2008 May 15;148C(2):147-53. Abstract

Genetic variation in human NPY expression affects stress response and emotion.

Zhou Z, Zhu G, Hariri AR, Enoch MA, Scott D, Sinha R, Virkkunen M, Mash DC, Lipsky RH, Hu XZ, Hodgkinson CA, Xu K, Buzas B, Yuan Q, Shen PH, Ferrell RE, Manuck SB, Brown SM, Hauger RL, Stohler CS, Zubieta JK, Goldman D, Nature. 2008 Apr 24;452(7190):997-1001. Abstract

It is time to take a stand for medical research and against terrorism targeting medical scientists.

Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, Berman KF, Blair J, Braff DL, Brown ES, Calabrese JR, Carlezon WA, Cook EH, Davidson RJ, Davis M, Desimone R, Drevets WC, Duman RS, Essock SM, Faraone SV, Freedman R, Friston KJ, Gelernter J, Geller B, Gill M, Gould E, Grace AA, Grillon C, Gueorguieva R, Hariri AR, Innis RB, Jones EG, Kleinman JE, Koob GF, Krystal AD, Leibenluft E, Levinson DF, Levitt PR, Lewis DA, Liberzon I, Lipska BK, Marder SR, Markou A, Mason GF, McDougle CJ, McEwen BS, McMahon FJ, Meaney MJ, Meltzer HY, Merikangas KR, Meyer-Lindenberg A, Mirnics K, Monteggia LM, Neumeister A, O'Brien CP, Owen MJ, Pine DS, Rapoport JL, Rauch SL, Robbins TW, Rosenbaum JF, Rosenberg DR, Ross CA, Rush AJ, Sackeim HA, Sanacora G, Schatzberg AF, Shaham Y, Siever LJ, Sunderland T, Tecott LH, Thase ME, Todd RD, Weissman MM, Yehuda R, Yoshikawa T, Young EA, McCandless R, Biol Psychiatry. 2008 Apr 15;63(8):725-7. Abstract

Neural bases of different cognitive strategies for facial affect processing in schizophrenia.

Fakra E, Salgado-Pineda P, Delaveau P, Hariri AR, Blin O, Schizophr Res. 2008 Mar;100(1-3):191-205. Abstract

Individual differences in stressor-evoked blood pressure reactivity vary with activation, volume, and functional connectivity of the amygdala.

Gianaros PJ, Sheu LK, Matthews KA, Jennings JR, Manuck SB, Hariri AR, J Neurosci. 2008 Jan 23;28(4):990-9. Abstract

Neuroimaging: technologies at the interface of genes, brain, and behavior.

Bigos KL, Hariri AR, Neuroimaging Clin N Am. 2007 Nov;17(4):459-67, viii. Abstract

Serotonin transporter (5-HTTLPR) genotype and amygdala activation: a meta-analysis.

Munafò MR, Brown SM, Hariri AR, Biol Psychiatry. 2008 May 1;63(9):852-7. Abstract

Temporal stability of individual differences in amygdala reactivity.

Manuck SB, Brown SM, Forbes EE, Hariri AR, Am J Psychiatry. 2007 Oct;164(10):1613-4. Abstract

Activity in medial prefrontal cortex during cognitive evaluation of threatening stimuli as a function of personality style.

Rubino V, Blasi G, Latorre V, Fazio L, d'Errico I, Mazzola V, Caforio G, Nardini M, Popolizio T, Hariri A, Arciero G, Bertolino A, Brain Res Bull. 2007 Sep 28;74(4):250-7. Abstract

Long-chain omega-3 fatty acid intake is associated positively with corticolimbic gray matter volume in healthy adults.

Conklin SM, Gianaros PJ, Brown SM, Yao JK, Hariri AR, Manuck SB, Muldoon MF, Neurosci Lett. 2007 Jun 29;421(3):209-12. Abstract

Preference for immediate over delayed rewards is associated with magnitude of ventral striatal activity.

Hariri AR, Brown SM, Williamson DE, Flory JD, de Wit H, Manuck SB, J Neurosci. 2006 Dec 20;26(51):13213-7. Abstract

Serotonin transporter genotype (5-HTTLPR): effects of neutral and undefined conditions on amygdala activation.

Heinz A, Smolka MN, Braus DF, Wrase J, Beck A, Flor H, Mann K, Schumann G, Büchel C, Hariri AR, Weinberger DR, Biol Psychiatry. 2007 Apr 15;61(8):1011-4. Abstract

Developmental imaging genetics: challenges and promises for translational research.

Viding E, Williamson DE, Hariri AR, Dev Psychopathol. 2006;18(3):877-92. Abstract

Facial expressions of emotion reveal neuroendocrine and cardiovascular stress responses.

Lerner JS, Dahl RE, Hariri AR, Taylor SE, Biol Psychiatry. 2007 Jan 15;61(2):253-60. Abstract

Catechol O-methyltransferase val158met genotype and neural mechanisms related to affective arousal and regulation.

Drabant EM, Hariri AR, Meyer-Lindenberg A, Munoz KE, Mattay VS, Kolachana BS, Egan MF, Weinberger DR, Arch Gen Psychiatry. 2006 Dec;63(12):1396-406. Abstract

Genetics and the future of clinical psychiatry.

Hariri AR, Lewis DA, Am J Psychiatry. 2006 Oct;163(10):1676-8. Abstract

Prefrontal-hippocampal coupling during memory processing is modulated by COMT val158met genotype.

Bertolino A, Rubino V, Sambataro F, Blasi G, Latorre V, Fazio L, Caforio G, Petruzzella V, Kolachana B, Hariri A, Meyer-Lindenberg A, Nardini M, Weinberger DR, Scarabino T, Biol Psychiatry. 2006 Dec 1;60(11):1250-8. Abstract

Human choline transporter gene variation is associated with corticolimbic reactivity and autonomic-cholinergic function.

Neumann SA, Brown SM, Ferrell RE, Flory JD, Manuck SB, Hariri AR, Biol Psychiatry. 2006 Nov 15;60(10):1155-62. Abstract

Neuroimaging studies of serotonin gene polymorphisms: exploring the interplay of genes, brain, and behavior.

Brown SM, Hariri AR, Cogn Affect Behav Neurosci. 2006 Mar;6(1):44-52. Abstract

Neural basis of individual differences in impulsivity: contributions of corticolimbic circuits for behavioral arousal and control.

Brown SM, Manuck SB, Flory JD, Hariri AR, Emotion. 2006 May;6(2):239-45. Abstract

The G72/G30 gene complex and cognitive abnormalities in schizophrenia.

Goldberg TE, Straub RE, Callicott JH, Hariri A, Mattay VS, Bigelow L, Coppola R, Egan MF, Weinberger DR, Neuropsychopharmacology. 2006 Sep;31(9):2022-32. Abstract

Genetics of emotional regulation: the role of the serotonin transporter in neural function.

Hariri AR, Holmes A, Trends Cogn Sci. 2006 Apr;10(4):182-91. Abstract

Imaging genetics: perspectives from studies of genetically driven variation in serotonin function and corticolimbic affective processing.

Hariri AR, Drabant EM, Weinberger DR, Biol Psychiatry. 2006 May 15;59(10):888-97. Abstract

Serotonin.

Hariri AR, Brown SM, Am J Psychiatry. 2006 Jan;163(1):12. Abstract

Neural mechanisms underlying probabilistic category learning in normal aging.

Fera F, Weickert TW, Goldberg TE, Tessitore A, Hariri A, Das S, Lee S, Zoltick B, Meeter M, Myers CE, Gluck MA, Weinberger DR, Mattay VS, J Neurosci. 2005 Dec 7;25(49):11340-8. Abstract

Neuroimaging and human genetics.

Winterer G, Hariri AR, Goldman D, Weinberger DR, Int Rev Neurobiol. 2005;67:325-83. Abstract

Facial expressions of emotion reveal neuroendocrine and cardiovascular stress responses.

Lerner JS, Gonzalez RM, Dahl RE, Hariri AR, Taylor SE, Biol Psychiatry. 2005 Nov 1;58(9):743-50. Abstract

Neurophysiological correlates of age-related changes in working memory capacity.

Mattay VS, Fera F, Tessitore A, Hariri AR, Berman KF, Das S, Meyer-Lindenberg A, Goldberg TE, Callicott JH, Weinberger DR, Neurosci Lett. 2006 Jan 9;392(1-2):32-7. Abstract

Neural correlates of genetically abnormal social cognition in Williams syndrome.

Meyer-Lindenberg A, Hariri AR, Munoz KE, Mervis CB, Mattay VS, Morris CA, Berman KF, Nat Neurosci. 2005 Aug;8(8):991-3. Abstract

Variation of human amygdala response during threatening stimuli as a function of 5'HTTLPR genotype and personality style.

Bertolino A, Arciero G, Rubino V, Latorre V, De Candia M, Mazzola V, Blasi G, Caforio G, Hariri A, Kolachana B, Nardini M, Weinberger DR, Scarabino T, Biol Psychiatry. 2005 Jun 15;57(12):1517-25. Abstract

Variation in DISC1 affects hippocampal structure and function and increases risk for schizophrenia.

Callicott JH, Straub RE, Pezawas L, Egan MF, Mattay VS, Hariri AR, Verchinski BA, Meyer-Lindenberg A, Balkissoon R, Kolachana B, Goldberg TE, Weinberger DR, Proc Natl Acad Sci U S A. 2005 Jun 14;102(24):8627-32. Abstract

Functional changes in the activity of brain regions underlying emotion processing in the elderly.

Tessitore A, Hariri AR, Fera F, Smith WG, Das S, Weinberger DR, Mattay VS, Psychiatry Res. 2005 May 30;139(1):9-18. Abstract

5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression.

Pezawas L, Meyer-Lindenberg A, Drabant EM, Verchinski BA, Munoz KE, Kolachana BS, Egan MF, Mattay VS, Hariri AR, Weinberger DR, Nat Neurosci. 2005 Jun;8(6):828-34. Abstract

An fMRI investigation of race-related amygdala activity in African-American and Caucasian-American individuals.

Lieberman MD, Hariri A, Jarcho JM, Eisenberger NI, Bookheimer SY, Nat Neurosci. 2005 Jun;8(6):720-2. Abstract

A susceptibility gene for affective disorders and the response of the human amygdala.

Hariri AR, Drabant EM, Munoz KE, Kolachana BS, Mattay VS, Egan MF, Weinberger DR, Arch Gen Psychiatry. 2005 Feb;62(2):146-52. Abstract

Variation in GRM3 affects cognition, prefrontal glutamate, and risk for schizophrenia.

Egan MF, Straub RE, Goldberg TE, Yakub I, Callicott JH, Hariri AR, Mattay VS, Bertolino A, Hyde TM, Shannon-Weickert C, Akil M, Crook J, Vakkalanka RK, Balkissoon R, Gibbs RA, Kleinman JE, Weinberger DR, Proc Natl Acad Sci U S A. 2004 Aug 24;101(34):12604-9. Abstract

Neural correlates of facial affect processing in children and adolescents with autism spectrum disorder.

Wang AT, Dapretto M, Hariri AR, Sigman M, Bookheimer SY, J Am Acad Child Adolesc Psychiatry. 2004 Apr;43(4):481-90. Abstract

Brain-derived neurotrophic factor val66met polymorphism affects human memory-related hippocampal activity and predicts memory performance.

Hariri AR, Goldberg TE, Mattay VS, Kolachana BS, Callicott JH, Egan MF, Weinberger DR, J Neurosci. 2003 Jul 30;23(17):6690-4. Abstract

IGSP Faculty

Ahmad Hariri - Publications