Curated Collection of Yeast Transcription Factor DNA Binding Specificity Data Reveals Novel Structural and Gene Regulatory Insights
In Genome Biology, Raluca Gordân and colleagues analyze in vitro and in vivo transcription factor-DNA binding data reported in previous large-scale studies to generate a comprehensive, curated resource for S. cerevisiae.
Reduced Selective Constraint in Endosymbionts: Elevation in Radical Amino Acid Replacements Occurs Genome-Wide
In this PLoS One report, Jennifer Wernegreen tests the hypothesis that purifying selection against radical amino acid changes is less effective in two insect endosymbiont groups than in related bacteria.
You Never Call, You Never Write: Why Return of 'Omic' Results to Research Participants Is Both a Good Idea and a Moral Imperative
In Personalized Medicine, Misha Angrist argues in favor of full disclosure of genetic and other 'omic' data as a means to engage participants in science and the research enterprise and position them as better stewards of their own health and well-being.
Error Correction in Gene Synthesis Technology
In Trends in Biotechnology, Jingdong Tian and colleagues discuss new trends and promising strategies of error filtration, correction and prevention in de novo gene and genome synthesis.
A Densely Interconnected Genome-Wide Network of MicroRNAs and Oncogenic Pathways Revealed Using Gene Expression Signatures
In PLoS Genetics, Patrick Tan and colleagues in Singapore conclude that gene expression signatures can be used as surrogates of miRNA activity.
Functional Interaction Between Responses to Lactic Acidosis and Hypoxia Regulates Genomic Transcriptional Outputs
Xiaohu Tang, Joe Lucas and Ashley Chi have published a study in Cancer Research showing that a significant portion of the transcriptional response to hypoxia elicited in cancer cells is abolished by simultaneous exposure to lactic acidosis.
Erythrocyte Plasma Membrane-Bound ERK1/2 Activation Promotes ICAM-4-Mediated Sickle Red Cell Adhesion to Endothelium
Arthur Moseley is a collaborator on a report in Blood exploring the mechanism underlying adhesion of sickled red blood cells to the endothelium of blood vessels.
Changes in Gene Expression Associated with Reproductive Maturation in Wild Female Baboons
In Genome Biology and Evolution, Courtney Babbitt, Jenny Tung, Greg Wray and Susan Alberts suggest that adaptive change in the development of the primate ovary may be largely driven at the mechanistic level by selection on gene regulation.
A Genome-Wide Analysis of Open Chromatin in Human Tracheal Epithelial Cells Reveals Novel Candidate Regulatory Elements for Lung Function
Greg Crawford is a collaborator on a study in the journal Thorax using DNase I hypersensitivity mapping followed by deep sequencing to generate a map of open chromatin in primary human tracheal epithelial cells. | 
